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Acanthosis Nigricans

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Acute

What is Acanthosis Nigricans?

Acanthosis nigricans is a condition that causes areas of dark, thick velvety skin in body folds and creases. It typically affects the armpits, groin and neck. Acanthosis nigricans (ak-an-THOE-sis NIE-grih-kuns) tends to affect people with obesity.

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The main sign of acanthosis nigricans is dark, thick, velvety skin in body folds and creases. It often appears in the armpits, groin and back of the neck.

  • Cosmetic disfigurement.
  • Psychological distress.
  • Acanthosis nigricans is an independent risk factor for the presence of diabetes.
  • Complications associated with underlying disease, for example, obesity-associated complications.

Conditions that affect hormone levels – such as Cushing's syndrome, polycystic ovary syndrome or an underactive thyroid. taking certain medicines – including steroids or hormone treatments like the contraceptive pill. rarely, cancer – usually stomach cancer.

The risk of acanthosis nigricans is higher in people who have obesity. The risk is also higher in people with a family history of the condition, especially in families where obesity and type 2 diabetes are also common.

This can mean stopping any medicine that's causing the problem or treating diabetes and other health conditions. Losing weight will help acanthosis nigricans fade. If you're concerned about your weight, talk to your doctor before going on a diet. Doctors may prescribe creams or lotions that can help lighten the skin.

How is it diagnosed?

How is it diagnosed?

There's no specific treatment for acanthosis nigricans. Your care provider might suggest treatments to help with pain and odor, such as skin creams, special soaps, medications and laser therapy. Treating the underlying cause might help.

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How is it treated?

Treatment for acute myeloid leukemia is vital. It varies with the patient and stage of the disease. Treatment options include

  • Lighten skin color: Prescription creams, ointments, and gels.
  • Reduce skin thickness: Laser treatments.
  • Decrease odor and discomfort: Antibiotics you apply to the skin and antibacterial soaps.
  • Help clear the skin: Retinoids (may be a cream or pill).

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