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Biliary Atresia

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Acute

What is Biliary Atresia?

Biliary atresia is a condition in infants in which the bile ducts outside and inside the liver are scarred and blocked. Bile can't flow into the intestine, so bile builds up in the liver and damages it. The damage leads to scarring, loss of liver tissue and function, and cirrhosis.

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The symptoms of biliary atresia usually appear by the age of two to six weeks and include a yellowish coloration of the skin and whites of the eyes (jaundice), abnormally pale stools, and dark urine. Infants may also have swollen (distended) stomach and/or abnormal enlargement of the liver (hepatomegaly).

Complications of biliary atresia include failure to thrive link and malnutrition, cirrhosis and related complications, and liver failure. Without treatment, infants with biliary atresia would develop cirrhosis within 6 months and liver failure within 1 year

  • infections with certain viruses.
  • coming into contact with harmful chemicals.
  • problems with the immune system.
  • a problem during liver and bile duct development in the womb.
  • certain genes or changes in genes—called mutations—that may increase the chances of developing biliary atresia.
  • infections with certain viruses.
  • coming into contact with harmful chemicals.
  • problems with the immune system.
  • a problem during liver and bile duct development in the womb.
  • certain genes or changes in genes—called mutations—that may increase the chances of developing biliary atresia.

Prevention of biliary atresia is not possible because of the reason that either it occurs in the womb or within 2 to 4 weeks after birth

How is it diagnosed?

How is it diagnosed?

Doctors treat biliary atresia with a surgery called the Kasai procedure and eventually, in most cases, a liver transplant. Thanks to advances in treatment, more than 80 to 90 percent of infants with biliary atresia survive to adulthood.

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How is it treated?

Treatment for acute myeloid leukemia is vital. It varies with the patient and stage of the disease. Treatment options include

Biliary atresia cannot be treated with medication. A surgery called Kasai procedure (also known as a or hepatoportoenterostomy) creates a path of bile flow from the liver into the intestine. The surgeon removes the damaged ducts outside of the liver (called extrahepatic ducts).

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