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Cardiac Amyloidosis Program

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Cardiac Amyloidosis

What is Cardiac Amyloidosis Program?

Cardiac amyloidosis is quite rare and produces symptoms very similar to other heart diseases. It is, therefore, often misdiagnosed. The disease is more common in men than in women and is rarely seen in people under age 40.

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Amyloid protein deposits in the heart can lead to: Congestive heart failure. Symptoms include shortness of breath during activity or while at rest, fatigue, fluid buildup in the abdomen and legs, and difficulty lying flat at night. Heart rhythm abnormalities.

  • Congestive heart failure.
  • Fluid buildup in the abdomen (ascites)
  • Increased sensitivity to digoxin.
  • Sick sinus syndrome.
  • Atrial fibrillation or ventricular arrhythmias.
  • Low blood pressure and dizziness from excessive urination (due to medicine)

Cardiac amyloidosis is a disorder caused by deposits of an abnormal protein (amyloid) in the heart tissue. These deposits make it hard for the heart to work properly.

  • Family history.
  • Kidney dialysis.
  • Race.
  • Age. Most people diagnosed with amyloidosis are between ages 60 and 70.
  • Sex. Amyloidosis occurs more commonly in men.
  • Other diseases. Having a chronic infectious or inflammatory disease increases the risk of AA amyloidosis.

Most types of amyloidosis are not preventable, but managing your kidney disease may help you delay or avoid kidney failure. You may be able to prevent AA amyloidosis if your chronic inflammatory condition is treated early and the inflammation is kept under control.

How is it diagnosed?

How is it diagnosed?
  • The drug Tafamidis, which stabilizes the TTR protein and slows the production of amyloid.
  • Gene silencers that stop the production of the ATTR protein are approved for patients with familial amyloid polyneuropathy (hereditary form of ATTR that affects the nerves)
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How is it treated?

Treatment for acute myeloid leukemia is vital. It varies with the patient and stage of the disease. Treatment options include

  • Cardiac biopsy.
  • Cardiac magnetic resonance imaging (MRI)
  • Cardiac ultrasound (Echocardiography)
  • Cardiovascular nuclear medicine.
  • Chemotherapy.
  • Implantable cardioverter defibrillator (ICD)
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