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Cushing's Syndrome

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Acute

What is Cushing's Syndrome?

Too much cortisol can cause some of the main symptoms of Cushing syndrome — a fatty hump between the shoulders, a rounded face, and pink or purple stretch marks on the skin. Cushing syndrome also can cause high blood pressure or bone loss. Sometimes, it can cause type 2 diabetes.

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  • Weight gain in the trunk, with thin arms and legs.
  • Weight gain in the face.
  • A fatty lump between the shoulders.
  • Pink or purple stretch marks on the stomach, hips, thighs, breasts and underarms.
  • Thin, frail skin that bruises easily.
  • Slow wound healing.
  • Acne.
  • heart attack and stroke.
  • blood clots in the legs and lungs.
  • infections.
  • bone loss and fractures.
  • high blood pressure.
  • unhealthy cholesterol levels.
  • depression or other mood changes.
  • memory loss or trouble concentrating.

What causes Cushing disease? Cushing disease occurs when a pituitary adenoma, a noncancerous (benign) tumor on the pea-size pituitary gland, makes too much adrenocorticotropic hormone (ACTH). In response, the body's two adrenal glands, one atop each kidney, make too much cortisol.

Risk factors for Cushing's syndrome are adrenal or pituitary tumors, long-term therapy with corticosteroids, and being female.

Can Cushing's syndrome be prevented? The most common cause of Cushing's syndrome is the long-term use of high-dose corticosteroids. If you are taking corticosteroid medication, your doctor should monitor your cortisol levels closely. Unfortunately, you can't prevent Cushing's syndrome when it is caused by a tumour

How is it diagnosed?

How is it diagnosed?

Treatment depends on the cause and may include surgery, radiation, chemotherapy, or cortisol-reducing medicines. If the cause is long-term use of glucocorticoids to treat another disorder, your doctor will gradually reduce your dosage to the lowest dose that will control that disorder.

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How is it treated?

Treatment for acute myeloid leukemia is vital. It varies with the patient and stage of the disease. Treatment options include

If an ACTH-producing tumor isn't found, or if one can't be fully removed and Cushing syndrome continues, your health care provider may recommend removing the adrenal glands. This is called a bilateral adrenalectomy. This procedure immediately stops the body from making too much cortisol

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    Dr. Sapana Bothra Jain

    Professor & HOD

    Experience8years

    QualificationMBBS, MS (General surgery), MCh Endocrine and Breast Surgery (SGPGIMS Lucknow)

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