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Gigantism

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Acute

What is Gigantism?

Gigantism is a very rare condition that happens when a child or adolescent has high levels of growth hormone in their body, which causes them to grow very tall. Gigantism is treatable, but early diagnosis is crucial to prevent excessive height and other complications

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  • a large head.
  • a very noticeable forehead.
  • a jaw that seems to jut out.
  • unusual features of the face, such as a broad nose.
  • very large hands and feet, with thick fingers and toes.
  • more sweating than usual.
  • a very large appetite.
  • general weakness.
  • Mobility issues due to muscle weakness.
  • Osteoarthritis.
  • Peripheral neuropathy.
  • Sleep apnea.
  • Enlarged heart (cardiomegaly) and heart valve issues.
  • Metabolic complications such as Type 2 diabetes.

Acromegaly and gigantism are disorders of growth hormone hypersecretion. The most common cause is a growth hormone (GH) secreting adenoma in the pituitary gland. Gigantism occurs when growth hormone hypersecretion occurs before the fusion of the long bone epiphysis and is characterized by tall stature

Gigantism is a serious condition that is nearly always caused by an adenoma, a tumor of the pituitary gland. Gigantism occurs in patients who had excessive growth hormone in childhood. The pituitary tumor cells secrete too much growth hormone (GH), leading to many changes in the body.

Expand Section. Gigantism cannot be prevented. Early treatment may prevent the disease from getting worse and help avoid complications.

How is it diagnosed?

How is it diagnosed?

Treatments for gigantism include: Surgery — to remove or shrink the pituitary tumour. Radiotherapy — to slow the growth of the tumour and lower the levels of growth hormone. Drug therapy — to control levels of growth hormones, ease symptoms, and shrink the tumour.

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How is it treated?

Treatment for acute myeloid leukemia is vital. It varies with the patient and stage of the disease. Treatment options include

  • Surgery — to remove or shrink the pituitary tumour.
  • Radiotherapy — to slow the growth of the tumour and lower the levels of growth hormone.
  • Drug therapy — to control levels of growth hormones, ease symptoms, and shrink the tumour.
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