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Immunoglobulin G Deficiency

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Acute

What is Immunoglobulin G Deficiency?

An IgG deficiency is a health problem in which your body doesn't make enough Immunoglobulin G (IgG). People with IgG deficiency are more likely to get infections. When your body feels it is under attack, it makes special proteins called immunoglobulins or antibodies. These antibodies are made by the plasma cells.

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  • Sinus infections and other respiratory infections.
  • Gastrointestinal infections.
  • Ear infections.
  • Pneumonia.
  • Bronchitis.
  • Infections that result in a sore throat.
  • Rarely, severe and life-threatening infections.
  • Sinus infections and other respiratory infections.
  • Gastrointestinal infections.
  • Ear infections.
  • Pneumonia.
  • Bronchitis.
  • Infections that result in a sore throat.
  • Rarely, severe and life-threatening infections.
  • Aging.
  • Malnutrition.
  • Chemotherapy medicines and long-term corticosteroids.
  • Infections such as HIV.
  • Aging.
  • Malnutrition.
  • Chemotherapy medicines and long-term corticosteroids.
  • Infections such as HIV.

A blood test that measures immunoglobulin levels can diagnose IgG deficiency. It’s possible to have a normal level of total IgG, so the testing of the IgG subclasses is important. Tests can also be done on saliva and cerebrospinal fluid. But, a blood test is the most common.

How is it diagnosed?

How is it diagnosed?

They may need immunoglobulin therapy to help boost their immune system rather than relying on antibiotics to prevent infections. This therapy contains pooled IgG antibodies from healthy donors with normal immune systems. If you need this, you may get the medicine through an IV (intravenous) or as a shot.

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How is it treated?

Treatment for acute myeloid leukemia is vital. It varies with the patient and stage of the disease. Treatment options include

Currently, the accepted therapy for IgG deficiency is the intravenous administration of 300-600 mg/kg of IgG once every 3-4 weeks, or 100-200 mg/kg/wk subcutaneously. Higher doses have been shown to be more effective in reducing infections in patients with histories of chronic or recurrent sinopulmonary infections

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