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Liver Cancer (Paediatric Hematology Oncology)

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Acute

What is Liver Cancer?

Primary liver cancer is a disease in which malignant (cancer) cells form in the tissues of the liver. Cancer that forms in other parts of the body and spreads to the liver is not primary liver cancer. The liver is one of the largest organs in the body.

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  • Weakness and tiredness.
  • Pain in the abdomen.
  • Swelling of the abdomen due to a build-up of fluid (ascites)
  • Pain in the right shoulder.
  • Appetite loss and feeling sick.
  • Weight loss.
  • Yellowing of the skin and eyes (jaundice)
  • Pale bowel motions.

Hepatic complications of hepatocellular carcinoma include hepatic encephalopathy, portal vein thrombosis, worsening ascites, variceal bleeding, obstructive jaundice, and pyogenic liver abscess. Intraperitoneal bleeding is a life-threatening complication of HCC.

  • fatty liver disease or genetic disorders including haemochromatosis, or alpha 1-antitrypsin deficiency.
  • type 2 diabetes.
  • hepatitis B or C.
  • alcohol consumption.
  • obesity.
  • smoking tobacco.
  • exposure to certain chemicals.

You can lower your risk for developing liver cancer by following healthy lifestyle measures, such as regular exercise, controlling your weight, and eating a healthy diet with limited amounts of alcohol. It's also important to avoid infection with the hepatitis B and C viruses.

  • Chronic infection with HBV or HCV. Chronic infection with the hepatitis B virus (HBV) or hepatitis C virus (HCV) increases your risk of liver cancer.
  • Cirrhosis.
  • Certain inherited liver diseases.
  • Diabetes.
  • Nonalcoholic fatty liver disease.
  • Exposure to aflatoxins.

How is it diagnosed?

How is it diagnosed?
  • Total hepatectomy and liver transplant.
  • Partial hepatectomy.
  • Ablation.
  • Transarterial chemoembolization and targeted therapy with sorafenib as palliative therapy to relieve symptoms and improve quality of life.
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How is it treated?

Treatment for acute myeloid leukemia is vital. It varies with the patient and stage of the disease. Treatment options include

  • Total hepatectomy and liver transplant.
  • Partial hepatectomy.
  • Ablation.
  • Transarterial chemoembolization and targeted therapy with sorafenib as palliative therapy to relieve symptoms and improve quality of life.
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