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Patent Ductus Arteriosus

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Acute

What is Patent Ductus Arteriosus?

Patent ductus arteriosus is a persistent opening between the two main blood vessels leaving the heart. Those vessels are the aorta and the pulmonary artery. The condition is present at birth. Patent ductus arteriosus (PDA) is a persistent opening between the two major blood vessels leading from the heart.

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  • Poor weight gain.
  • Fast or hard breathing.
  • Frequent respiratory infections.
  • Trouble feeding or tiredness while feeding.
  • Heart murmur (a “whooshing” sound made by abnormal blood flow through the heart)
  • Heart failure.
  • Pulmonary edema (fluid in the lungs)
  • Endocarditis (inflammation and infection of the lining of the heart)
  • Pulmonary hypertension (high blood pressure in the blood vessels of the lungs)
  • Certain genetic conditions.
  • Fetal distress in the womb.
  • Family history of congenital heart conditions.
  • Infections in the mother or fetus during pregnancy, such as rubella.
  • Other pregnancy-related risk factors, such as smoking or taking certain medications.

Patent ductus arteriosus occurs more commonly in babies who are born too early than in babies who are born full term. Family history and other genetic conditions. A family history of heart problems present at birth may increase the risk for a PDA

Ibuprofen (IV or oral) probably decreases the risk of PDA on day 3 or 4 (typical RR 0.39, 95% CI 0.31 to 0.48; typical RD -0.26, 95% CI -0.31 to -0.21; NNTB 4, 95% CI 3 to 5; 9 trials; N = 1029) (moderate-quality evidence). In the control group, the spontaneous closure rate was 58% by day 3 to 4 of age

How is it diagnosed?

How is it diagnosed?

A baby may need medicine such as indomethacin (an anti-inflammatory) during these months to help close the connection, or water medicine (diuretics) to reduce the risk of fluid buildup. Larger connections usually need treatment with catheterization or surgery.

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How is it treated?

Treatment for acute myeloid leukemia is vital. It varies with the patient and stage of the disease. Treatment options include

It allows a repair to be done without open-heart surgery. During a catheter procedure, the health care provider inserts a thin tube into a blood vessel in the groin and guides it to the heart. A plug or coil passes through the catheter. The plug or coil closes the ductus arteriosus.

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