Rare and Genetic Kidney Diseases

Acute

What is Rare and Genetic Kidney Diseases?

ADPKD is a progressive disease, which means the symptoms tend to get worse over time. ADPKD is the most common type of inherited kidney disease. In the United States, about 1 in every 800 people have ADPKD and it is the fourth leading cause of kidney failure.

Fatigue – Because the kidney cannot filter waste, toxins can build up in the body. These can cause fatigue or extreme tiredness. Dark urine – Some rare kidney diseases cause bleeding, but sometimes this blood can be hard to see with the naked eye. Urine with visible blood may look red, brown, or darker than usual.

  • Diabetes.
  • Heart disease.
  • High blood pressure.
  • Kidney infections.
  • Kidney stones.
  • Alport syndrome.
  • Cystinosis.
  • Fabry disease.
  • Gitelman syndrome.
  • Tuberous sclerosis complex (TSC)
  • Nephronophthisis (NPHP)
  • Autosomal dominant polycystic kidney disease (ADPKD) An autosomal dominant inherited kidney disease characterized by the growth of numerous cysts in the kidneys.

Family history is the biggest risk factor for hereditary kidney disease. But other health problems may impact how severe your symptoms are and if you'll suffer complications like kidney failure. Conditions that increase risk include: Diabetes

A healthy, balanced diet can reduce your risk of kidney disease by keeping your blood pressure and cholesterol at a healthy level. A balanced diet should include: plenty of fruit and vegetables – aim for at least 5 portions a day. meals that include starchy foods, such as potatoes, wholegrain bread, rice or pasta.

How is it diagnosed?

How is it diagnosed?

While there's no cure, managing your hereditary kidney disease symptoms is crucial. At the UPMC Kidney Disease Center, we will work with you to slow the progression of your disease.

People with kidney disease should:

  • See your doctor regularly to control high blood pressure and blood sugar levels.
  • Stay hydrated. Drink plenty of water and avoid caffeine.
  • Contact your doctor right away if you have a bladder or kidney infection.
  • Talk with your doctor about safe pain-management drugs.
  • Exercise, control your weight, and eat healthy foods.

How is it treated?

Treatment for acute myeloid leukemia is vital. It varies with the patient and stage of the disease. Treatment options include

Renasight is a test to determine if there is a genetic cause for an individual's kidney disease or if there is an increased hereditary risk due to family history. The test uses a blood or saliva sample to test 385 genes associated with chronic kidney disease (CKD).

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